A fibrin sealant for perforated and preperforated corneal ulcers.
نویسندگان
چکیده
Fibrin sealant is used to close perforated or preperforated corneal ulcers. In addition to the usual advantages of cyanoacrylates it is degraded physiologically and provides a good support for corneal healing. Corneal grafting can be avoided when contraindicated or postponed when conditions allow. This technique has been successful in nine eyes of eight patients.
منابع مشابه
A fibrin-related line of research and theoretical possibilities for the use of fibrin glue as a temporary basal membrane in non-perforated corneal ulcers and in photorefractive keratectomy (PRK)-operated corneas.
PURPOSE To report a specific line of research developed at the University of São Paulo/Brazil on fibrin glue used for sealing corneal perforations and the perspectives of use on non-perforated corneal ulcers and photorefractive keratectomy-operated corneas. METHODS To describe fibrin glue manufacture, development of a device to test the glued perforated corneal area resistance, subsequent exp...
متن کاملAutologous fibrin membrane combined with solid platelet-rich plasma in the management of perforated corneal ulcers: a pilot study.
IMPORTANCE The combined use of autologous fibrin membrane and the eye platelet-rich plasma (E-PRP) clot could be considered as a new surgical alternative for the closure of corneal perforations. OBJECTIVE To evaluate the use of autologous solid platelet-rich plasma in combination with an autologous fibrin membrane as a surgical alternative for wound closure in perforated corneal ulcers. DES...
متن کامل[Intracameral fibrin glue in spontaneous corneal perforation].
CASE REPORT A 70-year-old male was referred to our department due to a herpetic corneal perforation in the left eye. The perforation was healed with intracameral fibrin tissue sealant (Tissucol(®)), an amniotic membrane, and a large diameter soft contact lens. Postoperatively there were complete dissolution of the fibrin sealant and closure of the perforation without endothelial damage. DISCU...
متن کاملSuperimposed Fungal Ulcer after Fibrin Glue Sealant in Infectious Corneal Ulcer
A healthy 27-year-old woman with a corneal ulcer underwent fibrin gluing with a bandage contact lens twice, due to an impending perforation. The ulcer lesion slowly progressed, unresponsive to topical antibiotics and amphotericin B. We removed the gluing patch and performed a corneal or scraping or biopsy with multiple amniotic membrane grafts to seal the thinned or perforated cornea. Three day...
متن کاملEffect of intracameral injection of fibrin tissue sealant on the rabbit anterior segment
PURPOSE To investigate the effect of intracameral injection of fibrin tissue sealant on the anterior segment structures in a rabbit model. METHODS One eye of 10 rabbits received an intracameral injection of fibrin tissue sealant with a thrombin concentration of 500 IU (TISSEEL), and the fellow eye received an intracameral injection of balanced salt solution as a control. The rabbits were foll...
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ورودعنوان ژورنال:
- The British journal of ophthalmology
دوره 73 9 شماره
صفحات -
تاریخ انتشار 1989